MY RESEARCH

I am Senior Lecturer, Obstetrics and Gynaecology and Maternal Fetal Medicine Subspecialist at University College Cork and spend approximately half my time working with researchers in Cork, Ireland and internationally to understand more about pregnancy and how to improve pregnancy outcomes and maternal health.

I received my PhD in 2012 for work investigating the aetiology and potential treatments for pre-eclampsia under the supervision of Professor Louise Kenny. During this time I also obtained a Masters in Epidemiology from the University of London and a Diploma in Clinical Education from the National University of Ireland, Galway.

I have over one hundred publications including a recently accepted first author publication in Circulation and a co-author publication in PLoS Medicine, two leading internationally renowned journals. Awards received include the SRI Early Career Investigator Awards (January 2020), Royal Academy of Medicine of Ireland Research award, the William Stokes Award from the Royal College of Physicians of Ireland and the Harold Malkins award from the Royal College of Obstetricians and Gynaecologists. In 2014, I received a Scholarship to attend the 64th Lindau Nobel Laureate Meeting as one of “600 most qualified young researchers” chosen internationally.

Between 2014 and 2017 I completed an NIHR Clinical Academic Fellowship in King’s College London where I achieved my first independent major grant with the NIHR examining the postpartum cardiovascular effects of pre-eclampsia. This will be the largest postpartum echocardiography multicenter study conducted internationally and will be published in 2020.

My main area of research is in long term maternal health following complicated pregnancy but I also am interested in clinical interventions to improve pregnancy outcome, medical device development, basic science of the placenta, stress and the microbiome.

I am Treasurer of the International Society for the Study of Hypertension in Pregnancy, advisor to the Action for Pre-eclampsia Charity and representative of the RCOG Maternal Medicine (including Hypertensive Disease) Clinical Studies group since 2014.

MY GOOGLE SCHOLAR PROFILE

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SELECTED PUBLICATIONS

I have published approximately 100 peer reviewed full papers, reviews and book chapters (a full publication list can be found on my Google Scholar profile: https://scholar.google.com/citations?user=lNa2gAMAAAAJ&hl=en ).

The following details some of my selected publications from the past 5 years:

Original research and systematic reviews

  • Masukume G, McCarthy FP, Russell J, Baker PN, Kenny LC, Morton SM, Khashan AS. Caesarean section delivery and childhood obesity: evidence from the growing up in New Zealand cohort. J Epidemiol Community Health. 2019 Oct 9. pii: jech-2019-212591. doi: 10.1136/jech-2019-212591. PMID: 31597672
  • McCarthy FP, Leon LJ, Kenan Direk K, Gonzalez-Izquierdo A, David Prieto-Merino D, Casas JP, Chappell LC. Preeclampsia and premature cardiovascular disease in a large UK pregnancy cohort of linked electronic health records: a CALIBER study. Circulation. 2019 Sep 24;140(13):1050-1060. doi: 10.1161/CIRCULATIONAHA.118.038080. Epub 2019 Sep 23. PMID: 31545680.
  • Maher GM, O’Keeffe GW, Dalman C, Kearney PM, McCarthy FP, Kenny LC, Khashan AS. Association between preeclampsia and autism spectrum disorder: a population-based study. J Child Psychol Psychiatry. 2019 Sep 17. doi: 10.1111/jcpp.13127. PMID: 31531876
  • Khashan AS, Evans M, Kublickas M, McCarthy FP, Kenny LC, Stenvinkel P, Fitzgerald T, Kublickiene K. Preeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study. PLoS Med. 2019 Jul 30;16(7):e1002875. doi: 10.1371/journal.pmed.1002875. eCollection 2019 Jul.PMID: 31361741
  • Leite DFB, Morillon AC, Melo Júnior EF, Souza RT, McCarthy FP, Khashan A, Baker P, Kenny LC, Cecatti JG. Examining the predictive accuracy of metabolomics for small-for-gestational-age babies: a systematic review. BMJ Open. 2019 Aug 10;9(8):e031238. doi: 10.1136/bmjopen-2019-031238. PMID: 31401613
  • Barrett PM, McCarthy FP, Kublickiene K, Evans M, Cormican S, Judge C, Perry IJ, Kublickas M, Stenvinkel P, Khashan AS. Adverse pregnancy outcomes and long-term risk of maternal renal disease: a systematic review and meta-analysis protocol. BMJ Open. 2019 May 5;9(5):e027180. doi: 10.1136/bmjopen-2018-027180. PMID: 31061049
  • Conti-Ramsden F, Gill C, Seed PT, Bramham K, Chappell LC, McCarthy FP. Markers of maternal cardiac dysfunction in pre-eclampsia and superimposed pre-eclampsia. Eur J Obstet Gynecol Reprod Biol. 2019 Apr 19;237:151-156. doi: 10.1016/j.ejogrb.2019.04.034. PMID: 31051418
  • Williamson RD, McCarthy FP, Kenny LC, McCarthy CM. Activation of a TLR9 mediated innate immune response in preeclampsia. Sci Rep. 2019 Apr 11;9(1):5920. doi: 10.1038/s41598-019-42551-w. PMID: 30976066
  • Masukume G, McCarthy FP, Baker PN, Kenny LC, Morton SM, Murray DM, Hourihane JO, Khashan AS. Association between caesarean section delivery and obesity in childhood: a longitudinal cohort study in Ireland. BMJ Open. 2019 Mar 15;9(3):e025051. doi: 10.1136/bmjopen-2018-025051. PMID: 30878984
  • Williamson R, McCarthy FP, Kenny L, McCarthy C. Exploring the role of mitochondrial dysfunction in the pathophysiology of pre-eclampsia. Pregnancy Hypertens. 2018 Jul;13:248-253. doi: 10.1016/j.preghy.2018.06.012. Epub 2018 Jun 18. PMID: 30177060
  • Gallagher C, McCarthy FP, Ryan RM, Khashan AS. Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study. Autism Dev Disord. 2018 Jun 13. doi: 10.1007/s10803-018-3626-6. PMID: 29948531
  • Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice. International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertension. 2018 Jul;72(1):24-43. PMID: 29899139
  • Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. International Society for the Study of Hypertension in Pregnancy (ISSHP). Pregnancy Hypertens. 2018 May 23. pii: S2210-7789(18)30126-0. doi: 10.1016/j.preghy.2018.05.004. PMID: 29803330
  • Williamson R, McCarthy FP, Khashan A, Kenny L, McCarthy C. Investigating the role of mitochondrial dysfunction as a biomarker of pre-eclampsia.  Submitted Pregnancy Hypertension October 2017
  • McCarthy FP, Gill C, Seed PT, Bramham K, Chappell LC, Shennan AH. Performance of commercially available Placental growth factor tests in women with suspected preterm pre-eclampsia; the COMPARE study. Ultrasound Obstet Gynecol. 2018 Mar 25. doi: 10.1002/uog.19051. PMID: 29575304
  • Norris T, McCarthy FP, Khashan, AS, Murray DM, Kiely M, Hourihane J O’B, Baker PN, Kenny, LC. Do changing levels of maternal exercise during pregnancy affect neonatal adiposity? Secondary analysis of the Babies After SCOPE: Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints (BASELINE) birth cohort (Cork, Ireland). BMJ Open. 2017 Dec 1;7(11):e017987. doi: 10.1136/bmjopen-2017-017987.PMID: 29196482
  • Dahly D, Li X, Smith H, Khashan AS, Murray D, Kiely M, Hourihane JO’B, McCarthy FP, Kenny LC, Kearney PM. On behalf of the SCOPE Ireland Cohort study and the Cork BASELINE Birth Cohort Study. Associations between maternal lifestyle factors and neonatal body composition in the Screening for Pregnancy Endpoints (Cork) cohort study. Int J Epidemiol. 2018 Feb 1;47(1):131-145. doi: 10.1093/ije/dyx221.PMID: 29136159
  • McCarthy FP, Adetoba A, Gill C, Braham K, Bertolaccini M, Girardi G, Burton G, Poston L, Chappell L. Urinary congophilia in women with preeclampsia and chronic kidney disease. Am J Obstet Gynecol. 2016 Apr 29. pii: S0002-9378(16)30139-9. doi: 10.1016/j.ajog.2016.04.041. PMID: 27133010
  • McCarthy FP, Khashan AS, Kiely M, Murray D, Hourihan JO, Pasupathy D, Kenny LC. Parental physical and lifestyle factors and their association with newborn body composition. BJOG. 2016 Apr 22. doi: 10.1111/1471-0528.14042. PMID: 27102226
  • Murphy NM, McCarthy FP, Khashan AS, Myers JE, Simpson NA, Kearney PM, Greene RA, Poston L, Kenny LC. Compliance with National Institute of Health and Care Excellence risk-based screening for Gestational Diabetes Mellitus in nulliparous women. Eur J Obstet Gynecol Reprod Biol. 2016 Feb 8;199:60-65. doi: 10.1016/j.ejogrb.2016.01.044. PMID:26901398
  • Murphy A, McCarthy FP, McElroy B, Khashan AS, Spillane N, Marchocki Z, Sarkar RK, Higgins JR. Day care versus inpatient management of nausea and vomiting of pregnancy: cost utility analysis of a randomised controlled trial. Eur J Obstet Gynecol Reprod Biol. 2015 Dec 12;197:78-82. doi: 10.1016/j.ejogrb.2015.10.022. PMID: 26708475
  • McCarthy FP, Doyle A, Khashan AS, Kenny LC. Altered Maternal Plasma Glycogen Phosphorylase Isoenzyme BB as a Biomarker for Preeclampsia and Small for Gestational Age. Reprod Sci. 2015 Nov 26. pii: 1933719115616495. PMID: 26614266
  • Saccone G, Berghella V, Sarno L, Maruotti GM, Cetin I, Greco L, Khashan AS, McCarthy FP, Martinelli D, Fortunato F, Martinelli P.Celiac disease and obstetric complications: a systematic review and meta-analysis. Am J Obstet Gynecol. 2015 Sep 29. pii: S0002-9378(15)01194-1. doi: 10.1016/j.ajog.2015.09.080. PMID: 26432464
  • O’Keeffe LM, Kearney PM, McCarthy FP, Khashan AS, Greene RA, North RA , Poston L , McCowan LM, Baker PN, Dekker GA, Walker JJ, Taylor R, Kenny LC. Prevalence and predictors of alcohol use during pregnancy: findings from international multi-centre cohort studies. BMJ Open 2015;5:e006323.doi:10.1136/bmjopen-2014-006323. PMID: 26152324

See More on My Google Scholar Profile